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Depending on the type of rear differential in your 2006 Chevrolet Silverado 2500HD, you will need to use 75W-90 gear oil, but the capacity will vary. The 06 2500HD came with different rear differentials: 11.5 RG, 9.25 RG, 9.75 RG, 10.5 RG, 9.5 RG, or 8.6 RG. Depending on your model, you will use between 2.5 quarts (for the smallest 8.6 RG) and up to 3.27 quarts (for the largest 11.5 RG). It's best to identify your specific truck's rear differential before starting the fluid change since the capacities differ slightly.
In a 2006 Chevy 2500 HD, the amount of fluid that goes in the rear differential is 3 quarts.