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If you ever find yourself needing to reset the tire pressure monitoring system in your Lexus LS460, you'll have to do a little detective work. Depending on how tidy you are with your carpets, there's a physical reset button located under the dash, just above the accelerator pedal. The button is easy to spot with its icon and the word "SET." Keep in mind that a reset might not fix all issues, and you might have to replace one or more TPMS sensors if the problem is serious. Typically, an individual sensor for the LS460 will cost about $50, give or take $20. You can also find sets of four sensors online for $150 or less.
To reset the tire pressure sensor on a Lexus LS 460, you can do so by pressing and holding the TPMS reset button until the warning light flashes three times.