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The 2003 Mercedes-Benz ML350 requires 7.6 liters (8.0 quarts) of 0W-40 motor oil regardless of the engine size. When changing the oil along with a dry filter, you will need approximately 8.0 liters (8.5 quarts). SAE 0W-40 is a synthetic oil favored by European car manufacturers for its high performance and versatility in various climates. Mercedes recommends getting the oil changed in the ML350 every 7,500 miles, but you may need to do it more frequently based on your driving habits. If you want to do the maintenance yourself, popular 0W-40 oil options include Motul X-Max, Mobil 1, and Castrol Edge. Getting this service done at a dealership will likely cost between $170 and $200, with labor making up around $50 to $70 of that total.
Mercedes specifies that only 5w-30 full synthetic motor oil is suitable for use in the 2003 ml350.