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In your 2007 Toyota Sequoia, make sure to use SAE 75W90 gear oil in the rear differential as recommended by Toyota. It is advisable to opt for synthetic oil when it's time for an oil change. The oil in your differential is thicker than what's in your engine due to the compact space, leading to increased heat generation. Excessive heat can break down the oil quickly, so a thicker oil provides better protection. The differential contains the final set of gears before power is transmitted to the rear wheels of the vehicle.
The Toyota Sequoia requires synthetic 75w90 differential fluid for optimal performance.