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The Ford F-350 does not feature a special key for the spare tire. Instead, the spare tire is secured by a twist-off lock at the center of the tire along with the lug nuts. After unlocking the center and loosening the lug nuts, you can easily take out the spare tire.
In certain versions of the car, the key was connected to the lug wrench, while in others it was stored in the glove compartment. The dealership can assist you in resolving this matter.