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The 2015 Ford F-350 has a diesel exhaust fluid (DEF) tank that can hold approximately 5 gallons. It's recommended to use a Ford filler spout while filling to avoid overfilling or spilling, as it will automatically stop when reaching capacity. When you see the "low DEF" warning on your dashboard, this usually means there is about two gallons or less of DEF left in the tank. The inboard frame-mounted reductant tank holds 5.2 gallons, while the outboard frame-mounted reductant tank holds 5.73 gallons. The gauge inside the dashboard is limited in its accuracy and will only provide an exact reading when the DEF level is low. If you have more than half of the 5+ gallons in the tank, you won't get detailed information until it drops below half full.
The fuel tank for a Ford F-350 needs approximately 5 gallons of diesel and will need to be refilled when it reaches half empty.