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The auxiliary battery in a 2016 Mercedes E350 is situated near the spare tire in the trunk. Purchasing a replacement of similar kind will typically cost around $110 to $140 from most retail outlets. To install a new battery, start by removing the old one. Disconnect the negative and positive cables to access the bolts securing the battery. After removing the bolts, lift the battery out carefully as it is heavy. Place the new battery in position, secure it with bolts, reconnect the cables, and you're all set.
The additional battery in a 2016 Mercedes E350 can be found beside the spare tire stored in the trunk.