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Each of the eight trim levels of the 2017 Toyota Sienna is equipped with a 3.5L V6 engine that requires approximately 5.7 quarts of SAE 0W-20 full synthetic motor oil for an oil change. If you opt for the tow package, you will need slightly more oil, totaling just under 5.9 quarts per change. While SAE 5W-20 oil can technically be used, it is not advisable due to its lower viscosity. The numbers in the oil weight, such as the "0" or "5", indicate viscosity at startup temperature, while the "20" represents viscosity at operating temperature. Choosing an oil with lower numbers recommended by your manufacturer is always the best course of action to avoid potential premature engine wear.
The 2017 Toyota Sienna with a 3.5L V6 engine needs 5.7 quarts of 0W-20 synthetic oil, unless it has the tow package, in which case it takes 5.8 quarts.